The amount of compensatory sweating depends on the patient, the damage that the white rami communicans incurs, and the amount of cell body reorganization in the spinal cord after surgery.
Other potential complications include inadequate resection of the ganglia, gustatory sweating, pneumothorax, cardiac dysfunction, post-operative pain, and finally Horner’s syndrome secondary to resection of the stellate ganglion.
www.ubcmj.com/pdf/ubcmj_2_1_2010_24-29.pdf

After severing the cervical sympathetic trunk, the cells of the cervical sympathetic ganglion undergo transneuronic degeneration
After severing the sympathetic trunk, the cells of its origin undergo complete disintegration within a year.

http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0442.1967.tb00255.x/abstract

Wednesday, January 16, 2008

PROFOUND CHANGES IN CATECHOLAMINE CONTENT FOLLOWING SYMPATHECTOMY

These results indicate that
alterations in the relative abundance of TH mRNA mediate changes in TH activity induced by
chronic stress or sympathectomy, and that these changes require an intact sympathetic input.

Molecular adaptations in catecholamine biosynthesis induced
by cold stress and sympathectomy
M.K. Stachowiak 1, S.J. Fluharty 2, E.M. Stricker 2, M.J. Zigmond 3, B.B. Kaplan, Ph.D. 1 *
1
Department of Psychiatry, Center for Neuroscience, University of Pittsburgh, Pittsburgh,
Pennsylvania
2
Department of Psychology, Center for Neuroscience, University of Pittsburgh, Pittsburgh,
Pennsylvania
3
Department of Biological Sciences, Center for Neuroscience, University of Pittsburgh, Pittsburgh,
Pennsylvania





Epinephrine Produces a -Adrenergic
Receptor-Mediated Mechanical Hyperalgesia and
In Vitro Sensitization of Rat Nociceptors
Sachia G. Khasar, Gordon McCarter, and Jon D. Levine
Departments of Medicine and Oral and Maxillofacial Surgery, Division of
Neuroscience and Biomedical Sciences Program, National Institutes of Health
Pain Center (UCSF), University of California, San Francisco, California
94143-0440

SYMPATHECTOMY AND THE SUBMANDIBULAR GLAND

SYMPATHECTOMY CAUSES DEGENERATION OF THE SUBMANDIBULAR GLAND.

RIGOROUS TESTING FOR DRUGS, WHAT ABOUT SURGERIES???

I KNOW I AM REPEATING MYSELF AND YOU HAVE FOUND THIS QUESTION ALREADY SOMEWHERE ELSE, BUT I BELIEVE IT DESERVES ANOTHER TITLE, AND REMINDER.
HOW IS IS POSSIBLE THAT DRUGS HAVE TO GO THROUGH RIGOROUS TESTING BUT THE SAME DOES NOT APPLY TO IRREVERSIBLE NERVE SURGERIES??? WAIT A MINUTE! THIS IS THE TESTING!!!
I WISH SOMEBODY WOULD COLLECT THE RELEVANT DATA FOLLOWING SURGERY.
ANYBODY?!
AND: IF THIS IS THE TESTING, THEN THE PATIENT HAS TO BE INFORMED! IT IS CALLED INFORMED CONSENT.
HOW MANY RULES AND LAWS HAVE BEEN BROKEN HERE?!

WHAT ABOUT KUNTZ NERVE

Some surgeons generously throw in an additional nerve transection/ablation of the Nerve of Kuntz. It is interesting as there has been no study to investigate to exact function/role of this nerve or the effect of cutting this additional nerve in the short term and long term.
Another reason to call this a highly controversial and without doubt experimental surgery.

SYMPATHECTOMY INDUCES ADRENERGIC EXCITABILITY

Sympathectomy induces adrenergic excitability of cutaneous C-fiber nociceptors
DF Bossut, VK Shea, ER Perl
Department of Physiology, University of North Carolina at Chapel Hill,

Your doctor at the consultation might tell you that there is a tiny chance that something will go wrong during the surgery, and due to damage of the nerves and/or arteries you might experience pain. However this pain might be or become extreme.
Now, the fact is that you do not need extra damage to any other nerves during surgery. The surgery itself is the damage that will induce this pain.
And it has nothing to do with having the surgery performed by an experienced surgeon. NO difference. They all do the same: disrupt, damage, cut, burn or clamp the sympathetic chain.

The immuno-modulating effect of sympathectomy

coming soon...

EFFECT OF SYMPATHECTOMY ON BONE-RESORPTION

coming soon

CANNON'S LAW

ABOUT DENERVATION SUPERSENSITIVITY:
coming soon.

DOCUMENTARY ABOUT SYMPATHECTOMY

IF YOU ARE HERE IN AUSTRALIA AND ARE ONE OF THOSE WHO HAVE HAD THE SURGERY, AND HAVE EXPERIENCED MANY MEDICAL CONDITIONS AND ILLNESSES YOU DID NOT HAVE BEFORE, ARE STRUGGLING TO MANAGE THE 'COMPENSATORY SWEATING', THE REDUCED HEART RATE, DIZZINESS, COGNITIVE DIFFICULTIES, FATIGUE AND DEPRESSION, I AM INTERESTED IN YOUR STORY, AND WOULD LOVE TO HEAR FROM YOU.
THIS IS A STORY THAT NEEDS TO BE TOLD, THERE IS NO NEED TO BE SHY OR EMBARRASSED ABOUT IT. SILENCE ONLY PERPETUATES THE IGNORANCE AND THE CRIME.
THE OPERATION WILL CHANGE YOU! IT IS A CHANGE YOU HAVE NO CONTROL OVER AND YOU HAVE NOT CHOSEN. THAT IS THE VIOLATION OF YOU AS A HUMAN BEING. LOOSING YOUR SELF, YOUR SENSE OF SELF IS THE WORST KIND OF CRIME ONE CAN COMMIT AGAINST YOU.

THE PATHOPHYSIOLOGY OF SYMPATHECTOMY

M.Hashmonai
D.Kopelman

The pathophysiology of cervical
and upper thoracic sympathetic surgery
The main effect of upper thoracic sympathectomy is su-
domotor.To abolish sweating ofthe
palms,T2ganglionectomy
with the addition ofT3) was invari-
ably performed.To prevent axillary
sweating,additional T4ablation
was recommended.Sympathec-
tomy produces a vasodilatatory cu-
taneous effect.The circulation in
the muscles,however,is unaltered
or may even be reduced.It also ap-
pears that improved skin blood
flow is on the thermoregulatory,
not nutritive level.It seems that
chronic surgical sympathectomy
does not cause major changes in
the vascular function ofthe fore-
arm.Although the exact patho-
physiological mechanism ofblush-
ing is still obscure,bilateral upper
dorsal sympathectomy alleviates
this phenomenon.T2-T3gan-
glionectomy significantly decreases
pulse rate and systolic blood pres-
sure,reduces myocardial oxygen
demand,increases left ventricular
ejection fraction and prolongs Q-T
interval.A certain loss oflung vol-
ume and decrease ofpulmonary
diffusion capacity for CO result
from sympathectomy.Histomor-
phological muscle changes and
neuro-histochemical and biochem-
ical effects have also been ob-
served.
Key words sympathectomy ·
sudomotor effect · circulatory
effect · cardiac effect ·
thermoregulation

SYMPATHECTOMY=BETABLOCKER

Cardiovascular changes after bilateral upper dorsal sympathectomy. Short- and
long-term effects.

Papa MZ, Bass A, Schneiderman J, Drori Y, Tucker E, Adar R.
The effect of bilateral upper dorsal sympathectomy (UDS) on cardiac function was investigated in two groups of young healthy
patients who underwent bilateral excision of T2 and T3 ganglia for palmar hyperhidrosis. In ten patients echocardiography of
left ventricular function (LVF) was performed before operation and 2 weeks after operation. Electrocardiograms (ECG) were
done before operation, during operation immediately after sectioning each sympathetic chain, and at 2 weeks after operation.
The mean pulse rate decreased significantly in patients after they underwent bilateral UDS. There were no clinical arrhythmias
or changes in LVF in any patient. Submaximal exercise testing and ECG tracings done at rest and after effort were obtained for
29 patients before undergoing bilateral UDS, 30 days after operation, and 1-3 more times within a 2-year postoperative period.
Pulse rates taken at rest and after effort were significantly lower than those taken after operation, and the blood pressure
response to exercise was blunted. ECG tracings showed a significant change in the electrical frontal plane axis and shortening of
the QTc interval. These changes were evident 30 days after operation and persisted for 2 years. In conclusion, bilateral UDS has
no overt arrhythmogenic effect in the young, healthy heart and its beta-blocker-like effect persists for at least 2 years.

SYMPATHECTOMY FOR BLUSHING- MOST SEVERE SIDE-EFFECTS

As a standard procedure surgeons operate the patients by cutting or clamping the sympathetic chain at T2.
In the last 10 years there are more and more articles and presentations at conferences discouraging against this operation, as it is known to cause the most severe side-effects.

CEREBRAL DAMAGE

DISEASES OF THE CARDIOVASCULAR SYSTEM (SURGICAL) 1

the dangers of cerebral damage which may follow the use of the carotid or ..... years after sympathectomy was 41, whereas five years after sympathectomy ...
arjournals.annualreviews.org/doi/abs/10.1146/annurev.me.01.020150.000455 - Similar pages - Note this

Complications of Mediastinal Surgery

of the subclavian vein without revascularization may lead to transient upper ... The development of cerebral edema after thoracoscopic. sympathectomy is ...
doi.wiley.com/10.1002/9780470988367.ch14

CEREBRAL REVASCULARIZATION - SYMPATHECTOMY

Journal of Vascular Surgery : THE SECOND DECADE: 1957-1966 ...

Interest in cerebrovascular revascularization began with the presentation on .... Aortic Blood Flow Following Lower Aortic Resection and Sympathectomy. ...

linkinghub.elsevier.com/retrieve/pii/S0741521496702136

MIA: THERE IS NO QUESTION ABOUT IT, SYMPATHECTOMY WILL HAVE AN EFFECT OF CEREBRAL BLOOD FLOW. IT WILL REDUCE IT INITIALLY AND FORCE THE BODY TO GROW NEW VESSELS IN ORDER TO SUPPLY THE SUFFICIENT BLOOD/OXYGEN TO THE BRAIN. HOWEVER THIS REORGANIZATION WILL HAVE AN EFFECT ON THE BRAIN'S FUNCTIONING, AND CAN HAVE ADVERSE EFFECTS ON COGNITIVE FUNCTIONING BY TURNING OFF SOME CELLS THAT ARE STARVED OF OXYGEN, JUST LIKE IT HAPPENS WHEN ONE HAS A STROKE. IT CAN ALSO LEAD TO CHANGES IN PERSONALITY.
MY RESEARCH INDICATES THAT IT IS THE FRONTAL CORTEX THAT IS AFFECTED MOST AND THE FUNCTIONS ASSOCIATED WITH IT. IT ALSO INVOLVES CHANGES IN THE AMYGDALA, DUE TO THE DENERVATION OF THIS REGION OF THE BRAIN, KNOWN TO RECEIVE IT'S INNERVATION FROM THE UPPER CERVICAL GANGLION ONLY. SAME APPLIES TO THE PITUITARY GLAND. YOU MIGHT WANT TO LOOK UP THE FUNCTION OF THESE. IT IS QUITE REVEALING. ALSO THERE ARE STUDIES ON THESE REGIONS OF THE BRAIN FOLLOWING SYMPATHECTOMY.

VISCERAL AND CEREBRAL INVOLVEMENT FOLLOWING SYMPATHECTOMY: DEATH AFTER SURGERY

Vascularisation of Ischemic Limbs in Severe Occlusive Arterial ...

Eight of the 12 patients underwent sympathectomy. One patient, considered to have visceral and cerebral involvement, died. PMID: 3798265, UI: 87094501 ...
bharat_kelkar.tripod.com/sixb.htm - 117k

SYMPATHECTOMY FOR CEREBRAL REVASCULARIZATION

Neurosurg Focus 20(6):E7, 2006
The history of neurosurgical procedures for moyamoya
disease
CASSIUSV. C. REIS, M.D., SAMSAFAVI-ABBASI, M.D., PH.D., JOSEPHM. ZABRAMSKI, M.D.,
SEBASTIÃON. S. GUSMÃO, M.D., PH.D., ROBERTF. SPETZLER, M.D.,
ANDMARKC. PREUL, M.D.
Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph’s Hospital and Medical
Center, Phoenix, Arizona; and Federal University of Minas Gerais, Belo Horizonte, Brazil
Almost 50 years of research on moyamoya disease (1957–2006) has led to the development of a variety of surgical
and medical options for its management in affected patients. Some of these options have been abandoned, others have
served as the basis for the development of better procedures, and many are still in use today. Investigators studying
moyamoya disease during this period have concluded that the best treatment is planned after studying each patient’s presenting symptoms and angiographic pattern.
The surgical procedures proposed for the treatment of moyamoya disease can be classified into three categories: direct arterial bypasses, indirect arterial bypasses, and other methods. Direct bypass methods that have been proposed are vein grafts and extracranial–intracranial anastomosis (superficial temporal artery–middle cerebral artery [STA–
MCA] anastomosis and occipital artery–MCA anastomosis). Indirect techniques that have been proposed are the following: 1) encephaloduroarteriosynangiosis; 2) encephalomyosynangiosis; 3) encephalomyoarteriosynangiosis; 4) multiple cranial bur holes; and 5) transplantation of omentum. Other options such as cervical carotid sympathectomy and superior cervical ganglionectomy have also been proposed. In this paper the authors describe the history of the development of surgical techniques for treating moyamoya disease.

AMPUTATION RATE HIGHER AFTER SYMPATHECTOMY WAS HIGHER IN FEMALES

Has the clinical definition of thromboangiitis obliterans changed ...

Amputation rate after sympathectomy was higher in females: 36% vs 22%. A revascularization procedure was performed in 15 (0.6%) ...
www.springerlink.com/index/U20N650672742U24.pdf

Changes in hemodynamics of the carotid and middle cerebral arteries following sympathectomy

http://stroke.ahajournals.org/cgi/content/full/33/5/1180

CEREBRAL ISCHEMIA FOLLOWING SYMPATHECTOMY

Thoracoscopic sympathectomy for symptomatic arterial obstruction ...

Two patients died during follow-up: 1 of myocardial infarction and 1 of cerebral ischemia, 24 and 32 months, respectively, after the operation. ...

ats.ctsnetjournals.org/cgi/content/full/74/3/885

International Journal of Cardiology : One of the most frequent ...

Nineteen of 344 (11.9%) patients died during follow-up due to cerebral ... After sympathectomy, in postoperative term, the retroperitoneal hematoma occurred ...
linkinghub.elsevier.com/retrieve/pii/S0167527306000854

ADVERSE EFFECT ON KIDNEY

Role of sympathetic neurons in biochemical and functional ...

These results indicate that neonatal sympathectomy has an adverse effect on the biochemical and functional development of the kidney. ...
jpet.aspetjournals.org/cgi/content/abstract/246/2/427 -


Related Articles, Links

Kidney function in essential hypertension before and after sympathectomy a.m. Peet.

HILDEN T.

PMID: 15396150 [PubMed - indexed for MEDLINE]

SKIN AND SYMPATHECTOMY

Sympathectomy Protects Denervated Skin from Graft-Versus-Host Disease
Mohamed A. Kharfan-Dabaja MDa, Claudio Anasetti MDa and James L.M. Ferrara MDb
a
Division of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute and University of South
Florida, Tampa, Florida
b
Departments of Pediatrics and Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
Available online 20 February 2007.

Translated: this means that sympathectomy reduces the skin immune responses. Not a good thing. There are some surgeons - who offer sympathectomy - who promise that it will aslo cure acne!!!! Quite the contrary. Your skin will have less resilience and more prone to infections as it will have a downregulated immue reponse. Just another 'euphemism' from the doctors, that is totally unsubstantiated and fraudulent.

MSAC ON SYMPATHECTOMY

The Medicare Benefits Schedule (MBS) has evolved over time in response to changes in medical practice. Medicare benefits are payable in respect of a medical service listed in the MBS where that service is:
  • provided by a medical practitioner, and
  • a clinically relevant service (generally accepted in the medical profession as being necessary for the appropriate treatment of the patient).

Medicare item 35003 relates to the performance of cervical or upper thoracic sympathectomy by any surgical approach (irrespective of whether it is conducted by open exposure or endoscopically). Sympathectomy has been listed on the MBS for over three decades, and permitted by any surgical approach since 1991.

The Medical Services Advisory Committee (MSAC) was established in 1998 to advise the Minister for Health and Ageing on the strength of evidence pertaining to new and emerging medical technologies and procedures in relation to their safety, effectiveness and cost-effectiveness and under what circumstances public funding should be supported. MSAC has never considered this procedure, as it was listed on the MBS prior to MSAC's formation, and is therefore not a 'new and emerging medical technology'.

The Government relies on the advice of the medical profession in relation to the clinical relevance of procedures already listed on the MBS. If the Royal Australasian College of Surgeons were to formally advise the Government that it no longer regards this procedure as being clinically relevant, the Government would take appropriate action in relation to the MBS.

Symathectomy - controversial procedure

THE ROYAL COLLEGE OF AUSTRALASIAN SURGEONS DECLARES THAT ENDOSCOPIC THORACIC SYMPATHECTOMY IS A CONTROVERSIAL PROCEDURE, WITH NO INDEPENDENT STUDIES TO SUPPORT THE SAFETY OR EFFECTIVENESS OF THE SURGERY.

Insurance companies do not insure surgeons for sympathectomy

Yes, hard to believe but surgeons have to be forced in this way to discontinue performing the operation as it cost insurance companies too much money. These cases are settled before it has a chance to go to court and have some publicity. The people who decide to take the payments have to do so in exchange of a gag order. They can never speak about the operation. Not to anybody, anywhere, in any form. This kind of silencing and secrecy is perpetuating the surgeons ability to sell and perform the surgery on the unsuspecting and misinformed patient.
At least there is some change in Australia, but not all insurance companies have the same policy.
In the meantime many people fall victim to the euphemism and ignorance of the surgeons and end up having a procedure that was a predecessor of lobotomy.
It is the medical scandal of this century!!!!
I never thought that the insurance companies will play the role of protecting the patient from potentially harmful procedures. Isn't that the of the medical profession and government agencies overseeing medical procedures. Somebody failing the patients here!

Sympathectomy (coverage will not be provided for this procedure)
www.avant.org.au/public/pdf/Standard_Policy_Application_Form.pdf -

Monckeberg's sclerosis after sympathectomy

Monckeberg's sclerosis after sympathetic denervation in diabetic and non-diabetic
subjects.
Goebel FD, Fuessl HS.
Medial arterial calcification is frequently seen in diabetic patients with severe diabetic
neuropathy. Sixty patients (19 diabetic and 41 non-diabetic) were examined
radiologically for typical Monckeberg's sclerosis of feet arteries 6-8 years after uni- or
bilateral lumbar sympathectomy. Fifty-five out of 60 patients (92%) revealed medial
calcification. This calcification was observed in both feet of 93% of patients, who had
undergone bilateral operation. After unilateral sympathectomy the incidence of calcified
arteries on the side of operation was significantly higher than that on the contralateral
side (88% versus 18%, p less than 0.01). Although diabetic patients showed longer
stretches of calcification than non-diabetic subjects, the difference was not significant in
terms of incidence and length. Of 20 patients who had no evidence of calcinosis
pre-operatively, 11 developed medial calcification after unilateral operation exclusively
on the side of sympathectomy. In seven patients calcinosis was detected in both feet after
bilateral operation. In conclusion, sympathetic denervation is one of the causes of Monckeberg's sclerosis regardless of diabetes mellitus.
: Diabetologia. 1983 May;24(5):347-50.